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When used concurrently with insulin or insulin secretagogues such as sulfonylureas or meglitinides, the risk of hypoglycemia may be increased, particularly during the initiation of therapy or following dose escalations

While more research is needed to fully establish its long-term efficacy, current clinical experience has been highly positive

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Its antioxidant property also protects the skin from UV radiation and other environmental as well as internal stressors that generate free radicals that cause skin damage and hyperpigmentation

The studies documented that fat mass reduction occurred without corresponding changes in lean tissue mass

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