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Common adverse effects of Rybelsus include: Gastrointestinal symptoms : nausea, vomiting, diarrhoea, abdominal pain, and constipation (particularly during dose titration) Reduced appetite : which may be therapeutic but can be problematic in some patients Potential pancreatitis : rare but serious

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The medication is not suitable for individuals with a history of seizures or severely compromised kidney function

The sensitivity and subgroup analyses were performed on matched groups unless stated otherwise

Nat Rev Endocrinol (2010) 6(12):68997