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A 2021 study in *Obesity* found that semaglutide users lost approximately 94% fat and 6% lean mass compared to placebo groups losing 76% fat and 24% lean massa modest advantage that assumes consistent resistance training and adequate protein intake

Results and length of time on the medication vary by client

Lilly is also studying the drug as a potential treatment for obstructive sleep apnea (OSA) and hypertension in adults with obesity

Variants in the GLP1R gene (like rs6923761) and the MC4R gene affect how strongly you respond to appetite-suppressing signals

For patients with persistent reflux symptoms despite 8 weeks of PPI therapy or those with alarm features, referral to gastroenterology for upper endoscopy may be warranted, consistent with American College of Gastroenterology guidelines

Rinse off the soap completely with lukewarm water