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Aroda VR, Aberle J, Bardtrum L, Christiansen E, Knop FK, Gabery S, et al

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The population-dependent requirement by cultured mammalian cells for metabolites which they can synthesize

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The B complex vitamins are integral to the synthesis of neurotransmitters and proper functioning of the central nervous system, and play a key role in the methylation and decarboxylation reactions necessary for the integrity and synthesis of DNA, proteins, phospholipids, monoamine, and catecholamine neurotransmitters [8,9,10]

Further, acute trimetazidine injection (5 or 10 mg/kg) significantly decreased ROS in cardiomyocytes in rats with myocardial infarction [173]