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The mice were housed at a constant temperature and humidity under a 12-h/12-h lightdark cycle with free access to standard food and water for at least 1 week prior to the beginning of the experimental procedures

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K., Gross M

Nevertheless, observational studies such as these cannot determine whether low levels of vitamin B12 were the cause of the weight gain or whether higher levels of vitamin B12 protected against lower levels

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The enzyme's size and structure create substantial barriers to effective delivery throughout the body