SIBO has been associated with dysfunctional intestinal motility, characterized by inadequate peristaltic action of gastrointestinal smooth muscle (171174), hypochlorhydria, and pancreatic exocrine insufficiency (175)
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Your experience will depend on: Your starting body weight and BMI Whether you reach higher doses without intolerable side effects How consistently you take the medication and follow lifestyle changes Diet quality and physical activity levels Genetic factors that influence metabolic health It is important to remember that clinical trials take place in structured, highly supported environments
Diagnosis requires careful clinical assessment, including detailed pain history, neurological examination, and sometimes specialized sensory testing to characterize the pain response patterns and identify underlying causes
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