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This, in turn, results in the production of IL-17C, a process that contributes to the propagation of inflammation in individuals suffering from IBD (92)

At the same time, it indirectly regulates ACC activity, achieving a high degree of coordination between fatty acid oxidation and mitochondrial energy metabolism

doi: 10.1021/ac058000a

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Continuous receptor activation isn't inherently superior to pulsed stimulation for compounds like Dihexa where the therapeutic effect derives from triggered structural changes rather than ongoing receptor occupancy