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Divide the bulk quantity into individual-use portions stored in separate sealed vials

To achieve the enrollment target for the substudy (approximately 100 participants), the main study was overenrolled ( n = 338 versus planned n = 300)

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The prefrontal cortex, which governs executive function and impulse control, shows altered glutamate dynamics following GLP-1 agonist administration

Tirzepatide works by targeting both GLP-1 and GIP receptors, resulting in greater weight loss and better glucose lowering than medications that target GLP-1 alone, said Isaacs

Trends in Cardiovascular Medicine, 33 (3), 159166