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No PT-141 was specifically designed to activate the same MC4R pathway that causes erections, so switching to PT-141 doesnt eliminate erectile effects

Acta 1830 33293349 10.1016/j.bbagen.2012.10.012 [DOI] [PubMed] [Google Scholar] Murphy S., Simmons M

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Retatrutide belongs in protocols examining GCGR biology in conjunction with incretin signaling, particularly hepatic metabolic pathways

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