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Further eligibility requirements included being treated with a stable maximum dose (or highest dose without side effects) of a renin-angiotensin system inhibitor (angiotensin-converting enzyme inhibitors or angiotensin II receptor blockers)

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At the same time, healthy bone tissue depends heavily on mechanical loading

The medication is typically initiated at 0.25 mg once weekly for four weeks (a non-therapeutic dose intended to improve gastrointestinal tolerability), then increased to 0.5 mg weekly

If youre suffering from RED-S, your body starts borrowing against itself to keep you going, a debt that can quietly build up until injury, bone loss, and hormone crashes happen