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Patients who increase their water intake to at least 810 glasses daily and ensure adequate salt and electrolyte consumption often report resolution of muscle-related symptoms within days

JAMA 275, 15491556

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However, dermatologists agree that its best used as a target spot treatment, not an all-over solution

Drucker DJ, Nauck MA (2006) The incretin system: glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors in type 2 diabetes

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