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5-Amino-1MQ acts intracellularly, targeting the NNMT enzyme to boost NAD+ and enhance fat cell metabolism

Tomb JF, White O, Kerlavage AR, Clayton RA, Sutton GG, Fleischmann RD, Ketchum KA, Klenk HP, Gill S, Dougherty BA, Nelson K, Quackenbush J, Zhou L, Kirkness EF, Peterson S, Loftus B, Richardson D, Dodson R, Khalak HG, Glodek A, McKenney K, Fitzegerald LM, Lee N, Adams MD, Hickey EK, Berg DE, Gocayne JD, Utterback TR, Peterson JD, Kelley JM, Cotton MD, Weidman JM, Fujii C, Bowman C, Watthey L, Wallin E, Hayes WS, Borodovsky M, Karp PD, Smith HO, Fraser CM, Craig Venter J (1997) The complete genome sequence of the gastric pathogen Helicobacter pylori

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78 H 123 N 23 O 23 S 2 AOD-9604 Mechanism of Action Models the C-terminal lipolytic domain of human growth hormone (residues 176191) with an added N-terminal tyrosine