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Prior to and after drug administration, blood and CSF samples were taken and analysed by radioimmunoassay

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Cyanocobalamin (Vitamin B12) - Contraindications

The GRADE assessment showed moderate certainty of evidence for the increase in serum vitamin B12 levels and low certainty of evidence for homocysteine reduction, both across all studies and within RCT-only and observational-only subgroups

RESULTS: Of the 101 patients administered hydroxocobalamin, 30 survived, 42 died (17 at the fire scene and 25 at the intensive-care unit), and survival status was not known in the remaining 29 patients