In an additional, 24-week, placebo-controlled factorial study of initial therapy with sitagliptin in combination with metformin, the adverse reactions reported (regardless of investigator assessment of causality) in 5% of patients are shown in Table 2

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Clinical studies underscore a weight loss range of 15 to 20 percent with lifestyle modifications, ranking semaglutide among the most effective weight loss medications
has received consulting fees from Boehringer Ingelheim and Novo Nordisk
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Front Psychiatry 10:97 Nicolau J et al (2022) Short term effects of semaglutide on emotional eating and other abnormal eating patterns among subjects living with obesity