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Researchers analyzed the records of about 45 million people with at least one inpatient or outpatient visit between 2011 and 2023 to determine trends in new GLP-1 receptor agonist prescribing

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We found serum from four individuals with HTG was less able to activate bLPL compared to serum from a typical patient pool (Figure 4)

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Fourth, regarding the microbiota-lipid-depression mediation hypothesis, human intervention data are scarcemost evidence [e.g., (8890) on lipid transformation] comes from germ-free mouse models, but the diversity of the human gut microbiota (e.g., ~1,000 species vs