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O'i gymharu ffurfiau llafar neu chwistrelladwy, gall fformwleiddiadau hufen leihau faint o gyffuriau sy'n mynd i mewn i'r llif gwaed systemig, a thrwy hynny leihau'r risg o adweithiau niweidiol systemig

| Vial Size | BAC Water for 5mg/mL | BAC Water for 2.5mg/mL | |-----------|----------------------|------------------------| | 5mg | 1.0mL | 2.0mL | | 10mg | 2.0mL | 4.0mL | | 20mg | 4.0mL | 8.0mL | At 5mg/mL, every 10 units on an insulin syringe equals 0.5mg of semaglutide

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