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In an in vivo study, the acute treatment with GLP-1 in female rats resulted in the increase of the amplitude of the preovulatory LH surge, likely by the activation of the kisspeptin hypothalamic system, a key regulator of the pulsatile release of GnRH from GnRH neurons [35]

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Furthermore, patients oxygenation continued to improve and his veno-venous extracorporeal membrane oxygenator was discontinued after 2 weeks

The WNT signaling pathway from ligand secretion to gene transcription: molecular mechanisms and pharmacological targets