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Our conclusions would also be strengthened by repeating our analysis with a control group, comparing patients who switched to semaglutide with those who remained on their index GLP-1 RA or who switched to a different GLP-1 RA, such as dulaglutide

ACS Omega 7 (16), 1369713703

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Even so, prior studies suggest that up to 65 % of patients discontinue them within a year, and discontinuation has been associated with weight regain and reduced cardiometabolic benefits

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