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The molecule loses biological activity through hydrolysis, oxidation, or aggregation while the solution still looks clear

The effects were modest, but the study suggested immune modulation might be part of the benefit

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Although the existence of mtNOS has been described in mitochondrial fractions from different organs, recent evidence in rat liver mitochondria has questioned the existence of mtNOS, minimizing the contribution of in situ NO generation within mitochondrial to the formation of peroxynitrite (Venkatakrishnan et al., 2009)

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