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Versus near-zero through intact skin under identical conditions 3

That decline tracks closely with the loss of firmness, slower repair, and thinning skin that many people notice over time

3 Watanabe F, Hashizume E, Chan GP, Kamimura A

However, problems occur when we are overwhelmed with too much oxidative stress or too many toxins

Serum CP, as the primary copper transport protein, reflects systemic copper status, inflammation, and oxidative stress

Long-term safety data from decades of cosmetic use provides reassurance - no pattern of delayed toxicity, cumulative adverse effects, or serious safety signals has emerged despite widespread and prolonged use