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abcam) in 20 mM HEPES (pH 7.4) and 1.0 mM C14 betaine micelle buffer were titrated with increasing concentrations of FITC-tagged IR domain-binding peptide (ITP) or FITC-tagged scrambled ITP
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2.7.2 Quantifying relative efficacy and biased agonism The data were fitted using an operational model of agonism added to GraphPad Prism to account for changes in agonist E max and pEC 50 (van der Westhuizen et al., 2014)
Ximelagatran versus warfarin for stroke prevention in patients with nonvalvular atrial fibrillation: a randomized trial
