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Clinical trials found about 13.6% average body weight reduction with the oral form and about 14.9% with the injection, though the trials weren't designed for a direct comparison

Many of them have been used in weight-loss teas, pills, and powders for decades, in some cases even longer than GLP-1 medications, yet they have never caused a true breakthrough in weight-loss treatment

We do not know the full picture of the mechanism(s) behind how GLP-1 receptor agonists increase the likelihood of pregnancy

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The FDA has not approved any transdermal patch delivery system for GLP-1 medications

Signs of an overdose might include severe nausea, vomiting, low blood sugar (hypoglycemia), and gastrointestinal disturbances