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The different approach can work for people whose bodies did not respond well to single-target treatments

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These results are consistent with prior studies showing that GLP-1R activation diminishes operant responding for diverse classes of reinforcers, including palatable foods, alcohol, and psychostimulants (Arans et al., 2023

But your baseline hydration should come from non-caffeinated sources

Friston KJ, Holmes AP, Poline JB, Grasby PJ, Williams SC, Frackowiak RS, et al

Iatrogenic dry eye disease: an eledoisin/carnitine and osmolyte drops study