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GLP-1s have reached mainstream, and Main Street, status: two in three U.S

IGF-1 LR3, or Insulin-Like Growth Factor-1 Long R3, is a synthetic peptide derived from IGF-1, which is a hormone naturally produced in the liver in response to growth hormone (GH) stimulation

Some of the GLP-1 medications may not be covered by insurance

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3 In the REIMAGINE 1 trial, the most commonly reported adverse events (AEs) were gastrointestinal (GI)-related, occurring in 33/62 (53%) participants in the CagriSema 2.4 mg/2.4 mg group, 28/63 (44%) participants in the CagriSema 1 mg/1 mg group, and 13/64 (20%) participants in the placebo group

Doctors can also help manage side effects by adjusting diet and lifestyle factors or recommending over-the-counter or prescription remedies