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Rats were bred in-house at the Pharmacology animal facility, School of Medicine, Zagreb, Croatia

Khunweeraphong, N

4.5 mg cohort 69.9 kg / BMI 23.2 (the leanest cohorts)

For reference, here's a typical ARA-290 protocol structure: Week 1: 2mg once daily (morning administration) Weeks 2-6: 4mg once daily (morning administration) Assessment: Evaluate response at week 4, continue if beneficial Duration: 6-12 weeks depending on indication The timing of administration may matter less than consistency

Most available evidence comes from laboratory and animal studies

An efficient magnetothermal actuation setup for fast heating/cooling cycles or long-term induction heating of different magnetic nanoparticle classes