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Post-marketing surveillance and pharmacovigilance databases occasionally report seizure events in patients using weight loss medications, but establishing causality versus coincidental occurrence remains challenging

The key distinction is that HSA/FSA funds can only cover medications with a valid medical prescriptionself-directed purchases without clinical oversight do not qualify

Ongoing monitoring is important, particularly for blood pressure and kidney function

In animal studies semaglutide caused thyroid C-cell tumors

Arch Dermatol 128:934940 Carney JA, Gordon H, Carpenter PC et al (1985) The complex of myxomas, spotty pigmentation, and endocrine overactivity

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