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doi: 10.1016/S0140-6736(19)31149-3 55 GastaldelliACusiKFernndez LandLBrayRBrouwersBRodrguez

Liver stress is characterized by the formation of poorly folded and unfolded proteins, producing an imbalance between the cellular demand for folding and maturation of proteins, which facilitates the accumulation of unfolded proteins in central cells of the liver (Yoshida, 2007)

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Variants in genes affecting cysteine metabolism, glutathione synthesis, and oxidative stress response can inform discussions with your provider about whether glutathione supplementation aligns with your genetic background

doi: 10.1099/00221287-136-12-2343 250 WilliamsL

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