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FIGURE 1 4 Research progress of extracellular vesicles from plant sources in reproductive medicine In recent years, EVs have been awarded the title of natural nanomedicine due to their natural targeting, low immunogenicity and biobarrier penetration ability, which has set off a research boom in regenerative medicine and disease treatment (Zeng et al., 2024), and provide green and efficient therapeutic solutions for reproductive disorders such as premature ovarian failure, recurrent implantation failures, and spermatogenic dysfunction (Shao et al., 2023

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Increased fission caused by the upregulation of proteins Fis1 and Drp1 normally promotes mitophagy [309]

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