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Approaches include redox interactions with high-valent metal ions (like Cu 2 and Fe 3 ), suppression of GSH synthesis using agents such as BSO, the use of nanozymes that mimic enzymatic activity, and direct GSH neutralization through molecular binding [18]

Natural approaches identify triggers and reduce inflammation

PCOS, endometriosis, and age-related fertility decline often go hand in hand with increased inflammation and cellular stress

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Oxidative stress, plant natural antioxidants, and obesity

Melasma hormonal pigmentation, often facial and symmetrical 2