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Copper peptides work through three mechanisms: VEGF-driven angiogenesis around follicles, TGF-1 inhibition to extend anagen phase, and lysyl oxidase activation for extracellular matrix reinforcement

2+ /calmodulin (CaM)-dependent protein kinase kinase/CAM-dependent protein kinase IV/Prolactin regulatory element binding (CaMKK/CaMKIV/PREB), increasing apolipoprotein AI (apo AI) mRNA and promoter expression, and increasing apo AI secretion, thereby mediating intracellular cholesterol efflux

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Voronina, S