Pharmaceutical companies are addressing these challenges through combination regimens and novel formulations aimed at improving tolerability
Concentrated isotonic powdered drink with added L-carnitine and L-glutamine Replaces fluid and other substances lost during exercise Particularly recommended for endurance sports Replaces water, electrolytes, carbohydrates and vitamins lost during exercise - nutrients essential for proper metabolic function during intense and prolonged training Isotonic drinks are used to replace energy, water and electrolytes, and are particularly suitable for endurance sports
In a study by Locharernkul et al, some patients who developed either carbamazepine- or phenytoin-induced SJS were noted to have been exposed, and demonstrated tolerance, to other antiepileptics (phenytoin, phenobarbital, valproic acid, carbamazepine, and/or lamotrigine)
2021;9(1):22-31 and Supplementary Appendix
Draw the Diluent: Using a sterile syringe, pull back your desired amount of bacteriostatic water
Nature 420 , 853859 (2002)