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Aronne LJ, Horn DB, le Roux CW, SURMOUNT5 Trial Investigators
doi: 10.1186/s12933-021-01417-0 [DOI] [PMC free article] [PubMed] [Google Scholar] 7
The peptide portion binds copper(II) ions with high affinity through its histidine and glycine residues, forming a stable complex that has shown remarkable activity in gene expression studies across many cell types
A screening code (like Z13.29) is used when a doctor is looking for a potential problem but hasn't found it yet
About 1 in 10 people aged 55 years and over are affected by PN, and the most common cause is diabetes
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