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10.1164/rccm.200909-1415OC 212 WorlitzschD.TarranR.UlrichM.SchwabU.CekiciA.MeyerK

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CFTR participates in spermatogenesis, and evidence suggests its involvement in seminiferous intratubular fluid control, maintenance of the bloodtestis barrier, and improvement in follicle-stimulating hormone signalling, among other functions

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39,43,46,47,48 Dosages used have ranged from 800 to 2000 mg per day in longer-term studies (212 weeks), with the highest dose seeing the largest reductions in homocysteine

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