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The frequency and amplitude of pulsatile episodes are maintained, unlike exogenous GH which suppresses pulsatility

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The recommended dosage in patients with mild (eGFR of 60 89 mL/min/1.73 m 2) or moderate renal impairment (eGFR of 30-59 mL/min/1.73 m 2) is the same as those with normal kidney function [ see Clinical Pharmacology (12.3)]

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