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Such ligand-induced dimerization model has been observed in the activation of c-MET by a bacterial c-MET agonistInlB 31 , as well as in the activation of many other RTKs, such as PDGFR and VEGFR 32,33

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Mez J, Daneshyar DH, Kiernan PT, Abdolmohammadi B, Alarez VE, et al