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In multiple randomized controlled trials, saffron extract has shown superior antidepressant effects compared to placebo and efficacy similar to antidepressant medication (Ghasemi 2014

Weeks 2-4 Through the first month, the documented expectation remains low

These are usually involving complex organic molecules which take part in the protein activity for instance, the transformation of inactive apoproteins into enzymes

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It also helps to improve the function of iron and folic acid in the body

doi: 10.1038/nrendo.2013.47