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doi: 10.1124/jpet.114.218735
GSSG functions as a hydrogen acceptor in the enzymatic determination of NADP+ and NADPH and can be a proximal donor in S-glutathionylation post translational modifications
BuonocoreDGrosiniMGiardinaSMichelottiACarrabettaMSeneciAet al
It should have a defensible medical purpose, an appropriate prescriber, a qualified sterile-compounding source and informed consideration of the evidence and risks
However, it did improve anxiety symptoms in the patients.[ref] A meta-analysis of clinical trials using 900 2700 mg/day showed that NAC may improve hearing loss (noise-induced).[ref] Keep in mind that these studies involved patients who were likely to have increased glutathione use
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