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These diverse molecular mechanisms collectively demonstrate that EED-induced reproductive toxicity results from systematic disruption of multiple, interconnected biological pathways rather than simple receptor binding events

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Consistent with elevated TGF expression, the levels of p-Smad2 (Fig

Regardless of how they are produced, synthesis of Put, Spd, and Spm thus competes for nitrogen equivalents with not only the urea cycle (when it is active), but also with NO and Agm production for direct neurotransmission (Figure 1)

It supports the production of neurotransmitters that are responsible for mood regulation, memory, and concentration