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Abo-Elmatty, Nehal S

Numerous studies have shown an increase of systemic oxidative stress markers in the lungs of cigarettes smokers and COPD patients without and with inherited AATD

They are not trying to do the same job, so one is not simply better than the other

Basic Clin Pharmacol Toxicol (2018) 122:55969

Although technically two copies of both genes (homozygous) would be worse, it is very uncommon, whereas the heterozygous C677T/1298C is much more commonly the worst case scenario I have double gene mutation homozygous hereditary hemochromatosis I have SEVERE CFS SEVERE FIBRO DEPRESSION ANXIETY BIPOLAR SEVERE MCS

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