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Liver Fat: Sanyal et al., 2024 (Nature Medicine) Sanyal, Kaplan, Fras, Brouwers, and colleagues reported a phase 2a, randomized, placebo-controlled trial in adults with metabolic dysfunction-associated steatotic liver disease (MASLD) in Nature Medicine in 2024 [6]

This combination of simultaneous lean-mass and fat-mass change is one of the more frequently cited findings distinguishing IGF-1 LR3 research from single-pathway compounds

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