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The MM shows variable color from black to red or white accompanied with asymmetric and irregular morphology (73)

Colorado has the lowest percentage of people in the U.S

The position this article takes, given those three valid critiques, is that the mechanism evidence is strong enough, the delivery evidence is biologically plausible enough, and the safety window is wide enough that the recommendation is defensible

Once effective, licensed compounding pharmacies can again prepare injectable forms for prescription patients

By months 2-3, significant improvement in overall skin tone becomes apparent, with stubborn spots continuing to fade gradually

doi:10.1038/s41366-025-01859-6 51