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2,3 The GLP-1 receptor agonists (GLP-1 RAs) including exenatide, liraglutide, semaglutide, and dulaglutide mirror these roles that are achieved through their interaction with GLP-1 receptors

These findings uncover a non-canonical mechanism of action for GLP-1 analogs, highlighting a specific microbiota-endocannabinoid metabolic pathway as a potential therapeutic target for depression.

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GLP-1 And GLP-1 Receptor Agonists (GLP-1RA) GLP-1 (Glucagon-like peptide-1) is a peptide hormone encoded by the glucagon-like gene of human islet and secreted by intestinal L cells

Mitochondrial function naturally declines with age, and it is directly linked to reduced energy, slower metabolism, and increased susceptibility to age-related diseases