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In particular, these recent efforts have shown that activated T cells depend on G6PD and PPP activity for fundamental processes related to effector function, ranging from metabolic reprogramming and ROS homeostasis, to biosynthesis of effector molecules and signal transduction ( Figure 1B-2 )

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Thats part of the problem, says Henry Ellis, a sports medicine surgeon and researcher at the University of Texas, Southwestern, in Dallas, Texas, who has written about BPC-157 for the American Orthopedic Society for Sports Medicine (AOSSM)

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Its mechanism is better described as pleiotropic and incompletely understood