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For instance, PubMed search revealed that both mitochondrial and peroxisomal 3-keto-acyl-CoA thiolases contain 2 Cys residues and 1 His residue in its active site [67], while these two isozymes share 37% structural identity [68]

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(4) Vladimir Khavinson, Francesca Diomede,Ekaterina Mironova, Natalia Linkova, et al (2020) AEDG Peptide (Epitalon) Stimulates Gene Expression and Protein Synthesis during Neurogenesis: Possible Epigenetic Mechanism Molecules, 2020 Jan 30, Volume 25 (Issue 3), Page 609

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Elevated levels of ROS, free mtDNA, and inflammatory factors in the follicular fluid during ovarian aging [312,313,314], indicate that mitochondria-driven inflammation may be closely associated with age-related decline in fertility [315]

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