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This was a small pilot study (6 participants) results are preliminary and require confirmation in larger trials

Another factor is reproducibility

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An unresolved issue is whether GSH-mediated copper buffering primarily delays cuproptotic initiation or fundamentally determines the threshold for mitochondrial proteotoxic collapse

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Potential role of the cAMP/PKA/CREB signalling pathway in hypoxic preconditioning and effect on propofolinduced neurotoxicity in the hippocampus of neonatal rats