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Proc Natl Acad Sci USA 106(39):1665716662 Jeong K, Kim K, Kim H, Oh Y, Kim SJ, Jo Y et al (2015) Hypoxia induces cyclophilin B through the activation of transcription factor 6 in gastric adenocarcinoma cells

Increased expression of ER stress, inflammasome activation, and mitochondrial biogenesis-related genes in peripheral blood mononuclear cells in major depressive disorder

While GLP-1 agonists are generally well-tolerated, there are certain contraindications and precautions to consider, such as: History of pancreatitis, diabetic retinopathy, thyroid cancer

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Each additional receptor target appears to enhance efficacy but also changes the side effect profile and mechanism of action

Parulekar, A