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Orlistat is also available on the NHS for weight loss

GLP-1 inhibits food intake and promotes satiety in healthy individuals and those with obesity and diabetes [33]

Both medications are administered as subcutaneous injections, typically once weekly

The therapeutic benefits, particularly in treating fatty liver disease, often outweigh potential risks when patients are properly monitored and maintain adequate hydration during treatment

These three mechanisms make retatrutide the most potent GLP-1 therapy currently in development, and the most potent