Acknowledgements This work was supported by the George Whipple Professorship, the National Natural Science Foundation of China (81902592, 82070785), Hunan Natural Science Foundation (2020JJ5884) and Hunan Province Young talents Program (2021RC3027)
Semaglutide is a potent GLP-1 receptor agonist developed to support patients with type 2 diabetes
Topical spironolactone is an important compounded option for female pattern hair loss, where oral finasteride and dutasteride are contraindicated
Since it only needs to be taken once a week, it can be easier for people to remember and adhere to their treatment plan
GLP-1 medications work by mimicking the GLP-1 hormone, which slows gastric emptying, signals satiety to the brain, and helps regulate blood sugar
Despite these advantages, the technology faces challenges such as high costs, limited yields, and the absence of bioactive and bio-functional enzymes necessary to produce stable and functional collagen [33, 34]