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The higher sensitivity of MDA-T32 and MDA-T68 cells to RSL3 treatment may be due to the fact that RSL3 was originally selected from the chemical screen that showed synthetic lethality against RAS mutation and active TERT expressing cells 26

Glutathione has been found more effective than other glutathione antioxidant since it acts within cells

Ann Rev Food Sci Technol

Both upregulated and downregulated proteins were computed in accordance with each network to conduct a pathway analysis and identify proteins associated with the pathways of interest ( We additionally used the hypothesis strategy GeneMANIA (freely available at to generate hypotheses regarding gene functions, calculate gene lists, and weight genes, the algorithm of which is designed to automatically weight networks based on the relevance to the gene set

PMCID: PMC2923283

In this chronic phase, it is thought that auto recovery is difficult (127)