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The mechanism that causes ochronosis with hydroquinone cytotoxic disruption of melanocytes leading to paradoxical pigmentation is absent with alpha arbutin's competitive inhibition approach

Abstract Alterations in excitatory neurotransmitters, involving the glutamate (Glu) and glutamine (Gln) cycle, as well as inhibitory neurotransmission, GABA, are implicated in the pathophysiology of autism spectrum disorder (ASD)